Oxycodone Dosage

Oxycodone Dosage

Tshuaj kho los ntawm Varixcare.cz. Hloov kho zaum kawg ntawm Lub Ib Hlis 28, 2021.

Siv rau qhov ua tau zoo hauv qab no: 5 mg/5 mL; 20 mg/ml; 5 mg; ua. 15 mg; 30 mg; 10 mg; 20 mg; 40 mg; 80 mg; 60 mg; 9mg; ib. 13.5 mg; 18 mg; 27 mg; 36 mg; 160 mg; 7.5mg ib



Cov neeg laus niaj hnub siv rau:

Cov Me Nyuam Me Me Li Cas rau:

Cov ntaub ntawv ntau ntxiv:

Cov Neeg Laus Li Qub Rau Qhov Mob

Cov lus pom zoo noj tshuaj hauv qab no tsuas tuaj yeem txiav txim siab tawm tswv yim txog dab tsi yog qhov tseeb ntawm kev txiav txim siab kho mob nyob rau lub sijhawm

Tso tawm tam sim:
Raws li Thawj Opioid Analgesic: 5 txog 15 mg hais lus txhua 4 txog 6 teev
Kev daws qhov ncauj: Txhawm rau zam qhov ua yuam kev suav nrog suav tag nrho hauv mg thiab mL

Hloov los ntawm Lwm Qhov Chaw Opioids: Muaj qhov sib txawv ntawm cov neeg mob sib txawv hauv qhov muaj peev xwm ntawm cov tshuaj opioid thiab lawv cov qauv; thaum hloov cov neeg mob rau cov tshuaj no los ntawm lwm cov tshuaj opioids lossis thaum hloov pauv los ntawm cov khoom lag luam tswj hwm, nws yog qhov zoo tshaj kom tsis txhob xav txog cov tshuaj oxycodone thiab muab tshuaj kho kom zoo dua li ua kom ntau dhau thiab tswj kev siv tshuaj ntau dhau.

Lus tawm :
-Kev tshuaj yuav tsum yog tus kheej ib tus zuj zus txhawm rau muab qhov ua kom txaus txaus thaum txo qhov tsis zoo.
-Vim tias muaj kev pheej hmoo ntawm kev quav yeeb quav tshuaj, tsim txom thiab siv tsis raug, qhov ua tau zoo tshaj plaws rau lub sijhawm luv tshaj raws li cov hom phiaj kho tus neeg mob yuav tsum tau siv.
-Saib xyuas cov neeg mob ze rau kev nyuaj siab ua pa hauv thawj 24 txog 72 teev ntawm kev pib kho thiab tom qab ib qho kev nce ntxiv hauv koob tshuaj.

Siv: Rau kev tswj hwm qhov mob hnyav txaus kom xav tau tshuaj opioid analgesic thiab rau kev kho mob twg uas tsis txaus



Cov neeg laus niaj hnub siv rau mob hnyav

Cov lus pom zoo noj tshuaj hauv qab no tsuas tuaj yeem txiav txim siab qhia txog cov txheej txheem uas yog qhov ua tiav ntawm kev txiav txim siab kho mob nyob rau lub sijhawm

60 thiab 80 mg ncua-tso tawm (ER) ntsiav tshuaj, ib koob ntau dua 40 mg (36 mg oxycodone puag), tag nrho cov koob tshuaj txhua hnub ntau dua 80 mg (72 mg oxycodone puag), lossis siv 100 mg/5 mL (20 mg/mL) kev daws qhov ncauj yuav tsum txwv kom siv rau cov neeg mob opioid-tiv taus nkaus xwb

Ntev-tso tawm (ER):
Thawj koob tshuaj rau OPIOID-NAIVE thiab OPIOID NON-TOLERANT cov neeg mob:
-Oxycodone hydrochloride ER ntsiav tshuaj: 10 mg hais lus txhua 12 teev
-Oxycodone (puag) ER tsiav tshuaj: 9 mg hais lus txhua 12 teev nrog zaub mov

Kev tso tawm tam sim (IR):
-Qhov tshuaj thawj zaug rau cov neeg mob OPIOID-NAIVE: 5 txog 15 mg hais lus txhua txhua 4 txog 6 teev nyob rau ib puag ncig-teev-teev
-Kev daws qhov ncauj: Txhawm rau zam kev noj tshuaj yuam kev tag nrho koob tshuaj yuav tsum suav nrog mg thiab ml

MAINTENANCE: Kho tshuaj txhua txhua 1 txog 2 hnub raws li xav tau kom tau txais qhov sib npaug tsim nyog ntawm kev tswj qhov mob thiab opioid cuam tshuam txog kev phiv tshuaj; lub hom phiaj yuav tsum yog txhawm rau nrhiav qhov tshuaj qis tshaj plaws rau lub sijhawm luv tshaj raws li cov hom phiaj kho tus neeg mob
Qhov siab tshaj plaws txhua hnub: Oxycodone (puag) ER tsiav tshuaj: 288 mg raws li kev nyab xeeb ntawm cov khoom siv tsis tau tsim; qhov siab tshaj plaws ntawm cov tshuaj oxycodone hydrochloride tsis tau tsim

ZOO TSHAJ PLAWS ntawm OXYCODONE HYDROCHLORIDE rau OXYCODONE BASE:
-Oxycodone hydrochloride 10 mg = Oxycodone puag 9 mg
-Oxycodone hydrochloride 15 mg = Oxycodone puag 13.5 mg
-Oxycodone hydrochloride 20 mg = Oxycodone puag 18 mg
-Oxycodone hydrochloride 30 mg = Oxycodone puag 27 mg
-Oxycodone hydrochloride 40 mg = Oxycodone puag 36 mg

Lus tawm :
-Kev siv cov koob tshuaj pib siab dua hauv cov neeg mob uas tsis tiv taus opioid tuaj yeem ua rau muaj kev nyuaj siab ua pa nyuaj nrog thawj koob; xaiv thawj koob tshuaj yuav tsum coj mus rau hauv tus account qib opioid kam rau ua, tus neeg mob qhov xwm txheej, xwm txheej kev noj qab haus huv, tshuaj ib txhij, hom thiab qhov mob hnyav, thiab muaj feem cuam tshuam rau kev tsim txom, kev quav yeeb quav tshuaj, lossis kev hloov pauv.
-Opioid tiv taus cov neeg mob yog cov uas tau txais rau 1 lub lis piam lossis ntev dua: qhov ncauj morphine 60 mg/hnub; transdermal fentanyl 25 mcg/teev; qhov ncauj oxycodone 30 mg/hnub; qhov ncauj hydromorphone 8 mg/hnub; qhov ncauj oxymorphone 25 mg/hnub lossis koob tshuaj equianalgesic ntawm lwm opioid.
-Txhua yam khoom tso tawm tau tshwj tseg rau siv rau cov neeg mob uas muaj lwm txoj hauv kev kho mob (piv txwv li, tsis yog tshuaj opioid analgesics lossis tso tawm opioids tam sim) tsis muaj txiaj ntsig, tsis zam, lossis yuav tsis txaus los muab kev tswj kom txaus ntawm qhov mob; cov khoom no tsis yog npaj yuav siv raws li qhov xav tau (prn) analgesics.

-DOSE Hloov pauv los ntawm lwm cov tshuaj opioids yuav tsum ua kom zoo thiab nrog saib xyuas ze vim muaj kev hloov pauv loj ntawm cov neeg mob hauv opioid analgesic teb; sab laj txog kev hloov koob tshuaj rau cov lus pom zoo.

Siv: Rau kev tswj hwm qhov mob hnyav txaus kom xav tau txhua hnub, nyob ib puag ncig, kev kho mob opioid mus sij hawm ntev thiab rau qhov kev xaiv kho mob twg uas tsis txaus.

Kev Siv Menyuam Yaus Li Cas rau Mob Mob

Ua ntej yuav pib kho, cov neeg mob yuav tsum tau txais thiab zam lub opioids tsawg kawg 5 hnub sib law liag; rau 2 hnub tam sim ua ntej pib, cov neeg mob yuav tsum tau noj yam tsawg kawg ntawm 20 mg/hnub ntawm oxycodone lossis nws qhov sib npaug.
-Txhua tag nrho cov tshuaj opioid nyob ib ncig ntawm lub sijhawm thaum pib ua cov tshuaj oxycodone ER

11 xyoos lossis tshaj saud: Txuas ntxiv-tso tawm (ER) ntsiav tshuaj nkaus xwb :
-Kev pib txhaj tshuaj: Ib nrab ntawm xam tag nrho cov tshuaj oxycodone txhua hnub hais lus txhua txhua 12 teev

DOSE LUS:
-Txhua yam tshuaj txhua hnub ntawm opioid ua ntej los ntawm kev hloov pauv hloov pauv (CF) muab hauv qab no kom tau txais cov tshuaj oxycodone hauv mg/hnub; faib cov tshuaj oxycodone mg/hnub los ntawm 2 kom tau txais 12-teev oxycodone ER koob tshuaj; yog tias yuav tsum tau hloov pauv, ib puag ncig nqis mus rau lub zog ntsiav tshuaj nyob ze tshaj plaws
-Rau ua ntej opioid siv OXYCODONE: Qhov ncauj CF yog 1
-Rau ua ntej opioid siv HYDROCODONE: Qhov ncauj CF yog 0.9
-Rau ua ntej opioid siv HYDROMORPHONE: Qhov ncauj CF yog 4; Parenteral CF yog 20*
-Rau ua ntej opioid siv MORPHINE: Qhov ncauj CF yog 0.5; Parenteral CF yog 3*
-Rau ua ntej opioid siv TRAMADOL: Qhov ncauj CF yog 0.17; Parenteral CF yog 0.2*
*Rau cov neeg mob tau txais koob tshuaj parenteral opioids siab dua, yuav tsum muaj kev tiv thaiv CF ntau ntxiv (piv txwv li, rau kev txhaj tshuaj tiv thaiv kab mob siab ntau, siv CF ntawm 1.5 hloov pauv CF ntawm 3)
CFs muab saum toj no hloov ua ntej siv opioid rau oxycodone ER ntsiav tshuaj; tsis txhob siv CF los hloov pauv los ntawm oxycodone ER ntsiav tshuaj mus rau lwm qhov opioid raws li ua li ntawd yuav ua rau kwv yees kwv yees ntawm cov tshuaj opioid tshiab thiab muaj peev xwm ua rau tuag ntau dhau.
Hloov pauv los ntawm TRANSDERMAL FENTANYL: Tshem thaj 18 teev ua ntej pib oxycodone ER ntsiav tshuaj; hloov ib qho 10 mg oxycodone ER ntsiav tshuaj txhua 12 teev rau txhua 25 mcg/hr fentanyl transdermal thaj; saib xyuas zoo thaum lub sijhawm hloov pauv vim tias muaj qhov ntsuas qis ntawm qhov kev hloov pauv no

Titration thiab Txij Nkawm:
-Txhua tus titrate rau ib koob tshuaj uas ua kom muaj kev ua kom txaus txaus thiab txo qis kev phiv tshuaj; kev hloov kho koob tshuaj tuaj yeem ua txhua txhua 1 txog 2 hnub; thaum qhov koob tshuaj tau nce qhia hauv chaw kho mob, nws tau qhia tias tag nrho cov tshuaj oxycodone txhua hnub tsis tau nce ntau dua 25% nyob rau ib lub sijhawm.

Lus tawm :
-Kev hloov pauv koob tshuaj yuav tsum tau ua kom zoo thiab nrog saib xyuas zoo vim qhov loj ntawm cov neeg mob hloov pauv hauv opioid analgesic teb; nws yog qhov zoo tshaj rau tus neeg mob lub sijhawm 24-teev qhov ncauj xav tau oxycodone thiab muab tshuaj kho kom zoo dua li ua kom siab dhau thiab tswj hwm qhov tshwm sim tsis zoo.
-Kev siv cov koob tshuaj pib siab dua hauv cov neeg mob uas tsis tiv taus opioid tuaj yeem ua rau muaj kev nyuaj siab ua pa nyuaj nrog thawj koob; xaiv thawj koob tshuaj yuav tsum coj mus rau hauv tus account qib opioid kam rau ua, tus neeg mob qhov xwm txheej, xwm txheej kev noj qab haus huv, tshuaj ib txhij, hom thiab qhov mob hnyav, thiab muaj feem cuam tshuam rau kev tsim txom, kev quav yeeb quav tshuaj, lossis kev hloov pauv.
-Extended-release oxycodone cov khoom tau tshwj tseg rau siv rau cov neeg mob uas muaj lwm txoj hauv kev kho mob (piv txwv li, tsis yog tshuaj opioid analgesics lossis tso tawm opioids tam sim) tsis muaj txiaj ntsig, tsis zam, lossis yuav tsis txaus los muab kev tswj kom txaus txaus cov khoom no tsis yog npaj yuav siv raws li qhov xav tau (prn) analgesics.

Siv: Rau opioid-tiv taus tus menyuam yaus hnub nyoog 11 xyoos lossis laus dua uas twb tau txais thiab zam qhov tsawg kawg ntawm qhov ncauj opioid tsawg kawg oxycodone 20 mg/hnub lossis nws qhov sib npaug thiab leej twg mob hnyav txaus kom xav tau txhua hnub, nyob ib puag ncig -teev, kev kho mob opioid mus sij hawm ntev thiab rau qhov kev xaiv kho mob twg tsis txaus.



Kev Kho Mob Duav Li Qub

CrCl tsawg dua 60 mL/feeb: Pib tiv thaiv nrog qis dua li ib txwm tshuaj; titrate ua tib zoo xav tau cov nyhuv

Ntxiv-tso cov ntsiav tshuaj/tsiav tshuaj :
-Txhua yam kev ua kom loog yuav tsim nyog yog tias tus neeg mob tsis yog tus neeg sib tw rau qhov muaj zog tsawg tshaj plaws

Kev Kho Kho Mob Siab

Kev tsis zoo ntawm lub siab: Pib tiv thaiv nrog qis dua li ib txwm tshuaj; titrate ua tib zoo xav tau cov txiaj ntsig

Ntxiv-tso cov ntsiav tshuaj/tsiav tshuaj
-Qhov pib txhaj tshuaj: Ib feem peb txog ib nrab ntawm qhov ib txwm siv; titrate ua tib zoo xav tau cov txiaj ntsig
-Txhua yam kev ua kom loog yuav tsim nyog yog tias tus neeg mob tsis yog tus neeg sib tw rau qhov muaj zog tsawg tshaj plaws

Kev Kho Dose

Cov Neeg Laus, Cachectic, lossis Cov Neeg Tsis Txaus Siab:
Siv nrog kev ceev faj feem ntau pib ntawm qhov qis kawg ntawm qhov ntau npaum li cas, titrate maj mam thaum saib xyuas ze rau cov tsos mob ntawm CNS lossis ua pa nyuaj siab.
-For Extended-release products: Xav txog thawj zaug txhaj ib feem peb mus rau ib nrab qhov pom zoo pib koob tshuaj; titrate ua tib zoo

Ua tib zoo siv CNS depressants:
-Yog hais tias pib siv tshuaj tua kab mob opioid hauv tus neeg mob twb tau noj benzodiazepine lossis CNS kev nyuaj siab: qis dua thawj zaug ntawm cov tshuaj opioid analgesic tau pom zoo; titrate raws li cov lus teb kho mob
-Yog tias CNS kev nyuaj siab lossis benzodiazepine xav tau hauv tus neeg mob twb tau siv tshuaj opioid analgesic: pib nrog txo qis thawj zaug ntawm benzodiazepine lossis lwm yam kev nyuaj siab CNS; titrate raws li cov lus teb kho mob

Kev siv CYP450 3A4 inducers lossis inhibitors ib txhij yuav xav tau kev hloov kho tshuaj: Tham nrog kev cuam tshuam nrog tshuaj

DOSE hloov pauv mus rau ncua-tso tawm (ER) TABLETS lossis CAPSULES
-Kev hloov pauv koob tshuaj yuav tsum tau ua kom zoo thiab nrog saib xyuas zoo vim qhov loj ntawm cov neeg mob hloov pauv hauv opioid analgesic teb; txiav tawm tag nrho lwm yam nyob ib ncig ntawm lub moos opioid tshuaj thaum pib kho ER

Hloov pauv los ntawm Lwm Qhov ORAL OXYCODONE FORMULATIONS :
-Kev tswj hwm ib nrab ntawm tag nrho cov tshuaj txhua hnub oxycodone hydrochloride li ER ntsiav tshuaj lossis ER tshuaj ntsiav hais lus txhua 12 teev

Hloov pauv los ntawm Lwm Yam Tshuaj OPIOIDS :
-Oxycodone hydrochloride ER ntsiav tshuaj: 10 mg hais lus txhua 12 teev
-Oxycodone (puag) ER tsiav tshuaj: 9 mg hais lus txhua 12 teev nrog zaub mov

Hloov pauv los ntawm TRANSDERMAL FENTANYL: Tshem tawm qhov hloov pauv fentanyl thaj thiab 18 teev tom qab pib oxycodone hydrochloride ER ntsiav tshuaj 10 mg (lossis oxycodone ER capsules 9 mg) hais lus txhua 12 teev rau txhua fentanyl transdermal 25 mcg/hr thaj; saib xyuas zoo vim tias muaj cov ntaub ntawv txwv kev paub nrog kev hloov pauv no

Hloov pauv los ntawm METHADONE: Kaw kev saib xyuas yog qhov tseem ceeb tshwj xeeb vim yog tshuaj txiav yeeb ntev ib nrab-lub neej

QHOV TSEEB ntawm Kev Kho Mob hauv Tus Neeg Mob Lub Cev:
-Taper koob tshuaj maj, los ntawm 25% txog 50% txhua txhua 2 rau 4 hnub
-Saib xyuas cov cim thiab cov tsos mob ntawm kev tshem tawm; yog tias lawv tshwm sim, nce qhov koob tshuaj rau qib dhau los thiab ua kom qeeb dua
-Tsis txhob maj nrawm txiav txim rau tus neeg mob lub cev



Cov kev ceev faj

Tebchaws Asmeskas FDA xav tau Kev Ntsuam Xyuas Risk and Mitigation Strategy (REMS) rau txhua qhov opioids npaj rau kev kho mob sab nrauv. FDA tshiab Opioid Analgesic REMS yog tsim los pab hauv kev sib txuas lus txog qhov txaus ntshai ntawm kev siv tshuaj kho mob opioid rau cov neeg mob thiab cov kws saib xyuas kev noj qab haus huv. Nws suav nrog phau ntawv qhia tshuaj thiab cov khoom kom ntseeg tau tias muaj kev nyab xeeb siv. Yog xav paub ntxiv: www.accessdata.fda.gov/scripts/cder/rems/index.cfm

US BOXED WARNINGS: RISK OF MEDICATION ERRORS; ADDICTION, YUAV TSUM MUAJ NTUJ; RISK YUAV TSUM PAUB THIAB TUS TSWV YIM (REMS); LIFE-THREATENING RESPIRATORY DEPRESSION; RAWS LI QHOV TSEEB; NEONATAL OPIOID WITHDRAWAL SYNDROME; thiab CYP450 3A4 Kev cuam tshuam thiab kev pheej hmoo los ntawm kev ua siab zoo siv nrog BENZODIAZEPINES LOSSIS LWM TUS CNS DEPRESSANTS :
-Risk of Medication Errors: Ua kom muaj tseeb thaum sau ntawv, xa tawm, thiab tswj hwm oxycodone qhov ncauj daws; kev siv tshuaj tsis raug vim tsis meej pem ntawm mg thiab mL, thiab lwm yam kev hais daws qhov ncauj oxycodone ntawm qhov sib txawv tuaj yeem ua rau muaj kev phom sij ntau dhau.
-Txoj kev quav yeeb quav tshuaj, tsim txom, thiab siv tsis raug: Oxycodone nthuav tawm cov neeg mob thiab lwm tus neeg siv rau kev pheej hmoo ntawm kev quav yeeb quav tshuaj, tsim txom, thiab siv tsis raug, uas tuaj yeem ua rau siv tshuaj ntau dhau thiab tuag. Ntsuas txhua tus neeg mob txoj kev pheej hmoo ua ntej yuav sau tshuaj thiab saib xyuas txhua tus neeg mob tas li rau kev txhim kho tus cwj pwm lossis cov xwm txheej no.
-Opioid Analgesic REMS: Kom ntseeg tau tias cov txiaj ntsig ntawm opioid analgesics ntau dua qhov txaus ntshai ntawm kev quav yeeb quav tshuaj, tsim txom, thiab siv tsis raug, yuav tsum muaj REMS rau cov khoom no. Raws li qhov xav tau ntawm REMS, cov tuam txhab tshuaj nrog pom zoo opioid cov khoom lag luam analgesic yuav tsum ua rau REMS-raws txoj kev kawm muaj rau cov kws kho mob. Cov kws saib xyuas kev noj qab haus huv raug txhawb kom ua tiav REMS-ua raws txoj haujlwm kev kawm; tawm tswv yim rau cov neeg mob thiab/lossis lawv cov neeg saib xyuas, nrog txhua daim ntawv sau qhia txog kev siv nyab xeeb, muaj kev pheej hmoo loj, khaws cia, thiab pov tseg cov khoom no; hais qhia rau cov neeg mob thiab lawv cov neeg saib xyuas qhov tseem ceeb ntawm kev nyeem Phau Ntawv Qhia Tshuaj txhua lub sijhawm nws tau muab los ntawm lawv tus kws muag tshuaj, thiab txiav txim siab lwm yam cuab yeej los txhim kho tus neeg mob, tsev neeg, thiab kev nyab xeeb hauv zej zog.
-Life-Threatening Kev Nyuaj Siab Kev Nyuaj Siab: Ua rau muaj kev phom sij rau lub neej, lossis ua pa nyuaj siab ua rau tuag taus. Saib xyuas kev ua pa nyuaj siab, tshwj xeeb tshaj yog thaum pib lossis tom qab nce koob tshuaj. Qhia cov neeg mob kom nqos cov ntsiav tshuaj tag nrho; zuaj, zom, los yog yaj tuaj yeem ua rau tso sai thiab nqus tau cov tshuaj uas ua rau tuag taus.
-Accidental ingestion: Kev noj tsis raug ntawm txawm tias 1 koob tshuaj txuas ntxiv-tso tawm oxycodone, tshwj xeeb tshaj yog los ntawm menyuam yaus, tuaj yeem ua rau tuag ntau dhau.
-Tus me nyuam yug me nyuam Opioid rho tawm Syndrome: Kev siv sij hawm ntev thaum cev xeeb tub tuaj yeem ua rau tus menyuam yug menyuam opioid tshem tawm cov tsos mob, uas yuav ua rau muaj kev phom sij rau lub neej yog tias tsis lees paub thiab kho, thiab xav tau kev tswj hwm raws li cov txheej txheem tsim los ntawm cov kws paub txog menyuam yaus. Yog tias siv cov tshuaj opioid xav tau rau lub sijhawm ntev hauv tus poj niam cev xeeb tub, tus neeg mob yuav tsum tau qhia txog kev pheej hmoo ntawm tus menyuam yug menyuam opioid tshem tawm cov tsos mob thiab xyuas kom muaj kev kho kom haum.
-CYP450 3A4 Kev sib cuam tshuam: Kev siv ua ke nrog CYP450 3A4 inhibitors tuaj yeem ua rau oxycodone ntshav ntau ntxiv, uas tuaj yeem ua rau nce lossis ua rau cov tshuaj tsis zoo thiab tuaj yeem ua rau muaj kev nyuaj siab ua rau tuag taus. Ib qho ntxiv, kev tshem tawm ntawm kev siv CYP450 3A4 inducer tuaj yeem ua rau muaj kev nce ntxiv hauv oxycodone plasma concentration. Saib xyuas cov neeg mob tau txais oxycodone thiab ib qho CYP450 3A4 inhibitor lossis inducer.
-Concomitant Siv nrog Benzodiazepines lossis Lwm Yam Kev Nyuaj Siab Hauv CNS, suav nrog cawv, tuaj yeem ua rau mob tob tob, ua pa nyuaj siab, tsis nco qab, thiab tuag. Kev siv ua ke yuav tsum tau tseg rau cov neeg mob uas cov kev xaiv kho mob tsis txaus. Yog xav tau, txwv qhov koob tshuaj thiab lub sijhawm kom tsawg tshaj qhov xav tau thiab ua raws cov neeg mob rau cov cim thiab tsos mob ntawm kev ua pa nyuaj siab thiab ua kom lub siab nqig.

Kev txiav txim siab :
-Txoj kev nyuaj siab ua pa nyuaj
-Mob hawb pob lossis mob hawb pob loj heev lossis hypercarbia nyob rau qhov chaw tsis muaj neeg saib xyuas lossis thaum tsis muaj cov cuab yeej cawm tau
-Paub lossis xav tias mob plab zom mov, suav nrog tuag tes tuag taw ileus
-Hpersensitivity rau lub active yam los yog ib yam ntawm cov khoom xyaw

Kev nyab xeeb thiab ua tau zoo ntawm cov khoom tso tawm tam sim tsis tau tsim los rau cov neeg mob hnub nyoog qis dua 18 xyoo.

Kev nyab xeeb thiab ua tau zoo ntawm oxycodone ncua kev tso tshuaj ntsiav (Xtampza ER [R]) tsis tau tsim los rau cov neeg mob hnub nyoog qis dua 18 xyoo.

Kev nyab xeeb thiab ua tau zoo ntawm oxycodone ncua-tso cov ntsiav tshuaj (OxyContin ER [R]) tsis tau tsim los rau cov neeg mob hnub nyoog qis dua 11 xyoos.

Tham nrog WARNINGS ntu rau kev ceev faj ntxiv.

Tebchaws Asmeskas Cov Tshuaj Tiv Thaiv: Sijhawm II

Dialysis

Cov ntaub ntawv tsis muaj

Lwm Yam Lus

Cov lus qhia tswj hwm :
-Oxycodone qhov ncauj daws muaj 2 qhov sib xyaw (5 mg/mL thiab 20 mg/mL); kom tsis txhob ua yuam kev, nco ntsoov txheeb xyuas qhov koob tshuaj mg thiab ml thaum sau ntawv thiab xa tawm
-Cov ntsuas lub qhov ncauj ntsuas khob (5 mg/mL) lossis koob txhaj tshuaj hauv qhov ncauj (20 mg/mL) yuav tsum muab rau tus neeg mob thiab siv rau ntsuas

Cov ntsiav tshuaj tso tawm tam sim:
-Siv tag nrho nrog dej txaus kom ntseeg tau tias nqos tau

Cov ntsiav tshuaj txuas ntxiv:
-Nqis tag nrho; tsis txhob tawg, zom, zom, lossis tawg vim qhov no tuaj yeem ua rau tso tawm sai thiab nqus tau cov tshuaj uas ua rau tuag taus
-Tau nrog dej txaus kom ntseeg tau tias nqos tag nrho; tsis txhob pre-soak, lick lossis lwm yam ntub ua ntej nqos.

Ntxiv-tso tshuaj tsiav tshuaj:
-Txhua koob tshuaj nrog kwv yees tib yam zaub mov
Nqis tag nrho lossis qhib lub tsiav tshuaj thiab nchuav cov khoom rau hauv cov zaub mov muag lossis hauv lub khob, tswj ncaj qha rau hauv qhov ncauj thiab nqos tam sim ntawd; yaug qhov ncauj kom ntseeg tau tias tag nrho cov tshuaj ntsiav tau nqos.
Ib qho ntxiv, tswj hwm los ntawm lub raj nasogastric: yaug lub raj dej nrog dej, qhib lub tsiav tshuaj thiab ncuav microspheres ncaj qha mus rau hauv lub raj (tsis txhob muab cov tshuaj ntsiav tso ua ntej), yaug cov microspheres los ntawm lub raj nrog 15 ml dej; rov yaug dua 2 zaug nrog 10 ml dej txhua lub sijhawm kom ntseeg tau tias tsis muaj microspheres nyob hauv lub raj. Cov mis los yog kua mis yuav siv tau ua lub tsheb rau kev tswj hwm lossis yaug tawm los ntawm cov raj pub mis.

dav dav :
-Cov tshuaj no yuav tsum tau sau los ntawm kws saib xyuas kev noj qab haus huv uas paub txog kev siv cov tshuaj opioids muaj zog rau kev tswj hwm qhov mob.
-Ua rau kev pheej hmoo ntawm kev quav yeeb quav tshuaj, tsim txom, thiab siv tsis raug nrog opioids, txawm tias pom zoo koob tshuaj, thiab vim tias muaj kev pheej hmoo ntau dua ntawm kev siv tshuaj ntau dhau thiab tuag nrog ncua kev tso tawm cov tshuaj opioid, ncua kev tso tawm oxycodone yog siv rau cov neeg mob uas xaiv lwm txoj kev kho mob. cov kev xaiv (tsis yog opioid analgesics lossis tso tawm opioids tam sim) tsis muaj txiaj ntsig, tsis zam, lossis yuav tsis yog qhov tsis txaus los muab kev tswj hwm qhov mob txaus.
-Rau cov neeg mob tau txais lwm yam tshuaj opioid analgesics thiab hloov mus rau cov tshuaj no lossis mus rau qhov kev tso tawm ntev ntawm cov tshuaj no, nws muaj kev nyab xeeb dua rau kev saib tsis taus tus neeg mob 24-teev qhov ncauj yuav tsum tau thiab muab tshuaj kho kom nyab xeeb ntau dua li qhov xav tau thiab tswj kev tawm tsam tsis zoo; muaj qhov sib txawv ntawm cov neeg mob sib txawv hauv qhov muaj peev xwm txheeb ze ntawm cov tshuaj sib txawv opioid uas cov ntxhuav hloov pauv tsis tuaj yeem ntes.
-Thaum kho tus mob ntev, rov ntsuas dua qhov xav tau txuas ntxiv rau kev siv tshuaj tua kab mob opioid.

Saib xyuas :
-Saib xyuas kev nyuaj siab ua pa, tshwj xeeb tshaj yog thaum pib thiab ua raws li kev nce ntxiv hauv koob tshuaj; kev saib xyuas ze yuav tsim nyog rau cov neeg mob uas muaj kev pheej hmoo nce ntxiv thiab/lossis cov uas tau txais cov tshuaj sib xws uas ua rau muaj kev pheej hmoo ua pa nyuaj siab
-Saib xyuas cov cim qhia ntawm hypotension
Saib xyuas cov cim qhia tias cem quav
-Saib xyuas kev txhim kho tus cwj pwm uas qhia txog kev quav yeeb quav tshuaj, tsim txom, lossis siv tsis raug

Tus neeg mob cov lus qhia :
-Cov neeg mob yuav tsum tau qhia kom nyeem US FDA pom zoo Phau Ntawv Qhia Tshuaj txhua lub sijhawm cov tshuaj no raug xa tawm; lawv yuav tsum nkag siab txog kev siv nyab xeeb, muaj kev pheej hmoo loj, thiab khaws cia kom raug thiab pov tseg cov tshuaj no.
-Qhia cov neeg mob kom khaws cov tshuaj no kom nyab xeeb ntawm qhov pom thiab ncav cuag cov menyuam; kev siv los ntawm tus menyuam yog qhov xwm txheej kho mob thiab tuaj yeem ua rau tuag taus.
-Cov neeg mob yuav tsum nkag siab tias txawm tias tau ua raws li kev pom zoo, kev siv yuav ua rau muaj kev quav yeeb quav tshuaj, tsim txom, thiab siv tsis raug; qhia cov neeg mob kom tsis txhob faib lawv cov tshuaj nrog lwm tus thiab tiv thaiv lawv cov tshuaj los ntawm kev nyiag lossis siv tsis raug.
-Cov neeg mob yuav tsum tau qhia kom tshuaj xyuas nrog lawv tus kws kho mob ua ntej noj cov tshuaj tshiab, tshuaj ntsuab kho mob, thiab hla cov khoom lag luam muag khoom; cov neeg mob yuav tsum tsis txhob haus cawv thaum noj cov tshuaj no.
-Cov neeg mob yuav tsum nkag siab txog qhov txaus ntshai ntawm kev ua pa nyuaj siab rau lub neej, thiab yuav tsum ceeb toom thaum qhov kev pheej hmoo no loj tshaj plaws; cov neeg mob thiab cov neeg saib xyuas yuav tsum tau qhia kom tau txais kev pab xwm txheej tam sim yog tias siv tshuaj ntau dhau lossis yog muaj teeb meem ua pa.
-Cov neeg mob yuav tsum tau ua kom paub tias zom zaws, zom, lossis zom cov khoom lag luam nthuav tawm yuav ua rau tsis muaj kev tswj hwm ntawm oxycodone thiab tuaj yeem ua rau ntau dhau lossis tuag.
-Cov tshuaj no tuaj yeem ua rau tsaug zog, kiv taub hau, lossis ua rau lub siab xav lossis lub cev muaj zog; cov neeg mob yuav tsum zam kev tsav tsheb lossis siv lub tshuab ua haujlwm kom txog thaum muaj kev phom sij raug txiav txim.
-Cov poj niam ntawm cov menyuam muaj peev xwm tsim nyog yuav tsum nkag siab tias siv sijhawm ntev thaum cev xeeb tub tuaj yeem ua rau tus menyuam yug menyuam opioid tshem tawm cov tsos mob thiab yuav tsum tau lees paub thiab kho sai sai.

Cov ntaub ntawv ntxiv

Ib txwm sab laj nrog koj tus kws kho mob kom ntseeg tau tias cov ntaub ntawv tso tawm ntawm nplooj ntawv no siv rau koj tus kheej li xwm txheej.

Kev Tsis Pom Zoo Kho Mob