Phentermine

Phentermine

Lub npe: Phentermine hydrochloride hmoov
Daim ntawv noj tshuaj: ntsiav tshuaj
Hoob tshuaj: Anorexiants, cov CNS stimulants

Tshuaj kho los ntawm Varixcare.cz. Hloov kho zaum kawg thaum lub Plaub Hlis 1, 2020.



Ntawm Nplooj Ntawv no
Nthuav dav

Qhia thiab Siv

Phentermine Hydrochloride Tablets tau qhia tias yog lub sijhawm luv (ob peb lub lis piam) nyob rau hauv cov txheej txheem ntawm kev txo qhov hnyav raws li kev tawm dag zog, kev hloov kho tus cwj pwm thiab txwv tsis pub muaj caloric hauv kev tswj hwm kev rog dhau rau cov neeg mob nrog thawj lub cev hnyav ntsuas ≧ 30 kg/m2, lossis ≧ 27 kg/m2thaum muaj lwm yam kev pheej hmoo (piv txwv li, tswj ntshav siab, ntshav qab zib, hyperlipidemia).



Hauv qab no yog kab ntawv ntsuas lub cev qhov hnyav (BMI) raws ntau qhov siab thiab hnyav.

BMI yog xam los ntawm kev noj tus neeg mob qhov hnyav, hauv kilograms (kg), faib los ntawm tus neeg mob qhov siab, hauv metres (m), sib npaug. Kev hloov pauv metric muaj raws li hauv qab no: phaus ÷ 2.2 = kg; inches x 0.0254 = meters.



BODY MASS INDEX (BMI), kg/m2


Qhov muaj txiaj ntsig zoo ntawm cov neeg sawv cev ntawm chav kawm no, suav nrog Phentermine, [saib Clinical Pharmacology ( 12.1 , 12.2 )] yuav tsum ntsuas ntsuas qhov muaj peev xwm ua rau muaj feem cuam tshuam nrog lawv siv xws li cov tau piav qhia hauv qab no.

DOSAGE thiab ADMINISTRATION

Kev rog dhau

Kev siv tshuaj yuav tsum yog tus kheej kom tau txais cov lus teb txaus nrog qhov ua tau zoo tshaj plaws.



tshuaj dawb puag ncig r 153

Cov neeg laus niaj hnub noj tshuaj yog ib ntsiav tshuaj (37.5 mg) txhua hnub, raws li kws kho mob hais, ua ntej noj tshais lossis 1 txog 2 teev tom qab noj tshais. Qhov ntau npaum li cas tuaj yeem hloov kho rau tus neeg mob xav tau. Rau qee tus neeg mob, ib nrab ntsiav tshuaj (18.75 mg) txhua hnub tuaj yeem tsim nyog, thaum qee zaum nws yuav tsim nyog muab ib nrab ntsiav tshuaj (18.75 mg) ob zaug ib hnub.

Phentermine tsis pom zoo siv rau cov menyuam yaus hnub nyoog 16 xyoos.

Kev siv tshuaj yav tsaus ntuj yuav tsum zam vim tias muaj peev xwm ua rau muaj kev tsaug zog tsis txaus.

Dosage hauv Cov Neeg Mob Nrog Kev Xiam Oob Qhab

Qhov pom zoo ntau npaum ntawm Phentermine yog 15 mg txhua hnub rau cov neeg mob uas lub raum tsis zoo (eGFR 15 txog 29 mL/min/1.73m)2). Tsis txhob siv Phentermine hauv cov neeg mob nrog eGFR tsawg dua 15 ml/min/1.73m2lossis kab mob hauv lub raum kawg uas yuav tsum tau lim ntshav [saib Siv Hauv Cov Pej Xeem Tshwj Xeeb ( 8.6 ) thiab Clinical Pharmacology ( 12.3 )].

DOSAGE FORMS THIAB RAWS LI

Cov ntsiav tshuaj uas muaj 37.5 mg Phentermine hydrochloride (sib npaug rau 30 mg Phentermine puag).

Phentermine Hydrochloride Tablets, USP 37.5 mg yog cov dawb oval zoo li cov ntsiav tshuaj bisected nrog cov xim xiav, debossed nrog 810 ntawm ob sab sib cais.

Contraindications

  • Keeb kwm ntawm kab mob plawv (piv txwv li, kab mob hauv lub plawv, mob hlab ntsha tawg, lub plawv dhia tsis xwm yeem, lub plawv tsis ua haujlwm, tsis muaj kev tswj ntshav siab)
  • Lub sijhawm lossis hauv 14 hnub tom qab kev tswj hwm ntawm monoamine oxidase inhibitors
  • Hyperthyroidism
  • Glaucoma
  • Cov xeev ntxhov siab
  • Keeb kwm ntawm kev quav yeeb quav tshuaj
  • Cev xeeb tub [saib Siv Hauv Cov Pej Xeem Tshwj Xeeb ( 8.1 )]
  • Kev saib xyuas neeg mob [saib Siv Hauv Cov Pej Xeem Tshwj Xeeb ( 8.3 )]
  • Paub qhov ua tsis tau zoo, lossis tus yam ntxwv sib txawv rau cov amines sympathomimetic

Ceeb Toom thiab Ceev faj

Kev Koom Tes Nrog Lwm Yam Khoom Yeeb Tshuaj rau Kev Poob Haujlwm

Phentermine Hydrochloride Tablets tau qhia tsuas yog luv luv (ob peb lub lis piam) kev kho mob rau kev tswj hwm ntawm exogenous rog. Kev nyab xeeb thiab ua tau zoo ntawm kev sib xyaw ua ke nrog Phentermine thiab lwm yam khoom lag luam tshuaj rau kev poob phaus suav nrog cov tshuaj, tshuaj npaj tom khw, thiab tshuaj ntsuab, lossis tshuaj serotonergic xws li xaiv serotonin reuptake inhibitors (piv txwv li, fluoxetine, sertraline, fluvoxamine, paroxetine), tsis tau tsim. Yog li, kev tswj hwm ntawm Phentermine thiab cov khoom lag luam tshuaj no tsis pom zoo.

Thawj Pulmonary Hypertension

Primary Pulmonary Hypertension (PPH) - tsis tshua muaj, nquag ua rau tuag taus ntawm lub ntsws - tau tshaj tawm tias tshwm sim hauv cov neeg mob tau txais kev sib xyaw ntawm Phentermine nrog fenfluramine lossis dexfenfluramine. Qhov ua tau ntawm kev koom tes ntawm PPH thiab kev siv Phentermine ib leeg tsis tuaj yeem txiav tawm; muaj tsawg zaus ntawm PPH hauv cov neeg mob uas tshaj tawm tias tau noj Phentermine ib leeg.Thawj cov tsos mob ntawm PPH feem ntau yog ua pa nyuaj. Lwm cov tsos mob tshwm sim tuaj yeem suav nrog angina pectoris, syncope lossis qis qis qis. Cov neeg mob yuav tsum tau qhia kom qhia tam sim muaj qhov tsis zoo hauv kev ua kom lub siab ntev. Kev kho mob yuav tsum tsis ua txuas ntxiv hauv cov neeg mob uas tsim kho tshiab, cov tsos mob piav qhia tsis meej ntawm lub plawv dhia, angina pectoris, syncope lossis qis qis qis, thiab cov neeg mob yuav tsum raug tshuaj xyuas rau qhov muaj peev xwm ua rau muaj ntshav siab.

Mob plawv Valvular

Kev mob hnyav heev ntawm lub plawv mob plawv, feem ntau cuam tshuam rau mitral, aortic thiab/lossis tricuspid li qub, tau tshaj tawm hauv lwm tus neeg noj qab haus huv uas tau noj ua ke ntawm Phentermine nrog fenfluramine lossis dexfenfluramine kom poob phaus. Lub luag haujlwm ntawm Phentermine hauv keeb kwm ntawm cov valvulopathies no tsis tau tsim thiab lawv cov chav kawm hauv tib neeg tom qab cov tshuaj raug tso tseg tsis paub. Qhov ua tau ntawm kev koom tes ntawm kab mob plawv valvular thiab kev siv Phentermine ib leeg tsis tuaj yeem txiav tawm; tau muaj xwm txheej tsawg ntawm kab mob plawv hauv cov neeg mob uas tshaj tawm tias tau noj Phentermine ib leeg.

Kev Txhim Kho Kev Ua Siab Ncaj, Kev Txiav Txim Rau Hauv Kev Ua Siab Zoo

Thaum ua siab ntev rau cov txiaj ntsig anorectant txhim kho, qhov koob tshuaj pom zoo yuav tsum tsis pub dhau qhov kev sim ua kom muaj txiaj ntsig zoo; theej, cov tshuaj yuav tsum raug txiav.

Kev cuam tshuam rau Kev Muaj Peev Xwm los koom nrog Cov Haujlwm Ua Haujlwm Muaj Kev Nyab Xeeb

Phentermine yuav ua rau tus neeg mob lub peev xwm tuaj yeem koom nrog hauv cov dej num muaj kev phom sij xws li kev siv tshuab lossis tsav tsheb loj; yog li tus neeg mob yuav tsum tau ceeb toom raws li.

Kev pheej hmoo ntawm kev tsim txom thiab kev vam khom

Phentermine cuam tshuam txog kev siv tshuaj thiab tshuaj rau tshuaj amphetamine (d- thiab dll-amphetamine) thiab lwm yam cuam tshuam nrog cov tshuaj ua rau muaj kev tsim txom ntau. Qhov ua tau ntawm kev tsim txom ntawm Phentermine yuav tsum tau khaws cia hauv siab thaum ntsuas qhov tsim nyog ntawm suav nrog cov tshuaj raws li ib feem ntawm qhov kev pab cuam txo qhov hnyav. SaibKev Tsim Txom Tshuaj thiab Kev Ntseeg ( 9 )thiabTshaj dhau ( 10 ). .

Qhov tsawg kawg nkaus ua tau yuav tsum tau sau tseg lossis faib tawm ib zaug txhawm rau txo qis qhov muaj peev xwm ntawm kev siv tshuaj ntau dhau.

Pab Nrog Cawv

Kev siv cawv nrog Phentermine ua ke yuav ua rau muaj kev phiv tshuaj tsis haum.

Siv Hauv Cov Neeg Mob Ntshav Siab

Siv kev ceev faj hauv kev sau tshuaj Phentermine rau cov neeg mob txawm tias muaj qhov kub siab me me (kev pheej hmoo nce ntshav siab).

Siv hauv Cov Neeg Mob ntawm Cov Tshuaj Insulin lossis Qhov Ncauj Tshuaj Hypoglycemic rau Ntshav Qab Zib Mellitus

Kev txo qis cov tshuaj insulin lossis cov tshuaj hypoglycemic qhov ncauj hauv cov neeg mob ntshav qab zib mellitus tuaj yeem xav tau.

Cov Teeb Meem Tsis Zoo

Cov kev tsis zoo hauv qab no tau piav qhia, lossis piav qhia ntau ntxiv, hauv lwm ntu:

  • Thawj pulmonary hypertension [saibCeeb Toom thiab Ceev faj ( 5.2 )]
  • Kab mob plawv Valvular [saibCeeb Toom thiab Ceev faj ( 5.3 )]
  • Kev cuam tshuam rau kev muaj peev xwm koom nrog cov haujlwm uas muaj kev phom sij [saibCeeb Toom thiab Ceev faj ( 5.5 )]
  • Kev tshem tawm cov teebmeem tom qab kev tswj hwm qhov ntau npaum li cas ntev [saibKev Tsim Txom Tshuaj thiab Kev Ntseeg ( 9.3 )]

Cov kev tsis zoo hauv qab no rau Phentermine tau txheeb xyuas:

yog ibuprofen tib yam li tylenol

Mob plawv

Thawj cov ntshav siab thiab/lossis rov ua rau lub plawv mob plawv, ua rau lub plawv dhia, tachycardia, nce ntshav siab, xwm txheej ischemic.

Central Nervous System

Overstimulation, nyob tsis tswm, kiv taub hau, insomnia, euphoria, dysphoria, tshee, mob taub hau, puas siab puas ntsws.


Txoj hnyuv

Qhuav ntawm lub qhov ncauj, saj tsis zoo, raws plab, cem quav, lwm yam teeb meem hauv lub plab.

Ua xua

Kab mob urticaria.

Endocrine

Tsis muaj zog, hloov pauv libido.

Kev Sib Tham Tshuaj

Monoamine Oxidase Inhibitors

Kev siv Phentermine yog txwv tsis pub siv sijhawm lossis hauv 14 hnub tom qab kev tswj hwm ntawm monoamine oxidase inhibitors vim tias muaj kev pheej hmoo ntawm kev kub ntxhov.

Cawv

Kev siv cawv nrog Phentermine ua ke yuav ua rau muaj kev phiv tshuaj tsis haum.

Cov tshuaj insulin thiab qhov ncauj hypoglycemic tshuaj

Yuav tsum tau hloov kho [saibCeeb Toom thiab Ceev faj ( 5.9 )].

Adrenergic Neuron Thaiv Cov Tshuaj

Phentermine yuav txo qis cov nyhuv hypotensive ntawm adrenergic neuron thaiv cov tshuaj.

Siv HAUV TSEV NEEG POPULATIONS

Cev xeeb tub

Teratogenic Effects

Cev xeeb tub qeb X

Phentermine yog contraindicated thaum cev xeeb tub vim qhov poob phaus tsis muaj txiaj ntsig zoo rau poj niam cev xeeb tub thiab tuaj yeem ua rau menyuam hauv plab raug mob. Qhov hnyav nce yam tsawg kawg nkaus, thiab tsis poob phaus, tam sim no tau pom zoo rau txhua tus poj niam cev xeeb tub, suav nrog cov uas twb rog dhau los lossis rog dhau, vim yog qhov hnyav ntxiv uas tshwm sim hauv niam cov ntaub so ntswg thaum cev xeeb tub. Phentermine muaj cov tshuaj ua haujlwm zoo ib yam li amphetamine (d- thiab dll-amphetamine) [saibClinical Pharmacology ( 12.1 )]. Kev tshawb fawb txog kev tsim tsiaj tsis tau ua nrog Phentermine. Yog tias cov tshuaj no tau siv thaum cev xeeb tub, lossis yog tus neeg mob cev xeeb tub thaum noj cov tshuaj no, tus neeg mob yuav tsum tau ceeb toom txog qhov muaj peev xwm ua rau menyuam hauv plab.

Niam laus

Nws tsis paub yog tias Phentermine raug tso tawm hauv tib neeg cov mis; txawm li cas los xij, lwm cov amphetamines muaj nyob hauv tib neeg cov mis. Vim tias muaj peev xwm ua rau muaj kev phom sij loj hauv cov menyuam mos hauv tsev laus, kev txiav txim siab yuav tsum tau txiav txim siab tias yuav tsum tso tseg kev saib xyuas menyuam lossis tso tseg kev siv tshuaj, suav nrog qhov tseem ceeb ntawm cov tshuaj rau niam.

Kev Siv Menyuam Yaus

Kev nyab xeeb thiab ua tau zoo hauv cov neeg mob menyuam yaus tseem tsis tau tsim. Vim tias menyuam yaus rog dhau yog mob hnyav uas yuav tsum tau kho ntev, kev siv cov khoom no, pom zoo rau kev kho lub sijhawm luv, tsis pom zoo.

Kev siv Geriatric

Feem ntau, kev xaiv koob tshuaj rau cov neeg laus yuav tsum tau ceev faj, feem ntau pib ntawm qhov qis kawg ntawm qhov ntau npaum li cas, xav txog qhov ntau dua ntawm kev ua haujlwm tsis zoo ntawm lub siab, lub raum, lossis lub plawv, thiab mob sib thooj lossis lwm yam tshuaj kho mob.

Cov tshuaj no tau paub tias tau tso tawm ntau los ntawm lub raum, thiab qhov kev pheej hmoo ntawm cov tshuaj lom lom rau cov tshuaj no tuaj yeem ntau dua hauv cov neeg mob uas lub raum tsis ua haujlwm. Vim tias cov neeg mob laus dua tuaj yeem ua rau lub raum tsis ua haujlwm, yuav tsum tau saib xyuas hauv kev xaiv koob tshuaj, thiab nws yuav muaj txiaj ntsig los saib xyuas lub raum ua haujlwm.

Lub raum tsis zoo

Raws li qhov qhia tawm ntawm Phentermine hauv cov zis, kev nthuav tawm tuaj yeem xav tau hauv cov neeg mob uas lub raum tsis zoo [saibSoj ntsuamPharmacology ( 12.3 )].

Siv kev ceev faj thaum siv Phentermine rau cov neeg mob uas lub raum tsis zoo. Hauv cov neeg mob uas lub raum tsis zoo (eGFR 15 txog 29 mL/min/1.73m2), txwv qhov ntau npaum ntawm Phentermine rau 15 mg txhua hnub [saib Dosage thiab Administration ( 2.2 )]. Phentermine tsis tau kawm hauv cov neeg mob nrog eGFR tsawg dua 15 ml/min/1.73m2, suav nrog kab mob hauv lub raum kawg uas yuav tsum tau lim ntshav; zam kev siv cov neeg no.

Kev Tsim Tshuaj Yeeb Tshuaj thiab Kev Nyob Zoo

Tswj Tshuaj

Phentermine yog Teem Sijhawm IV tswj cov tshuaj.

Kev tsim txom

Phentermine muaj feem cuam tshuam txog tshuaj thiab tshuaj rau tshuaj amphetamines. Amphetamines thiab lwm yam tshuaj txhawb nqa tau raug tsim txom ntau thiab muaj peev xwm ua phem ntawm Phentermine yuav tsum tau khaws cia hauv siab thaum ntsuas qhov xav tau ntawm suav nrog cov tshuaj raws li ib feem ntawm qhov kev pab cuam txo qhov hnyav.

Kev vam khom

Kev tsim txom ntawm amphetamines thiab tshuaj muaj feem cuam tshuam nrog kev mob siab rau ntawm kev xav thiab kev ua haujlwm tsis zoo hauv zej zog. Muaj cov ntawv ceeb toom ntawm cov neeg mob uas tau nce qhov ntau npaum ntawm cov tshuaj no mus rau ntau zaus ntau dua li tau pom zoo. Kev txiav tawm sai sai tom qab kev tswj hwm qhov tshuaj ntau ntau ua rau qaug zog heev thiab muaj kev nyuaj siab nyuaj siab; kev hloov pauv tseem tau sau tseg ntawm kev pw tsaug zog EEG. Qhov tshwm sim ntawm kev qaug cawv ntev ntev nrog cov tshuaj anorectic suav nrog dermatoses hnyav, cim kev pw tsaug zog, chim siab, ua rau neeg tsis haum xeeb thiab hloov tus kheej. Qhov tshwm sim hnyav ntawm kev qaug cawv ntev ntev yog kev puas siab puas ntsws, feem ntau hauv tsev kho mob tsis paub qhov txawv ntawm tus mob schizophrenia.

Tshaj dhau

Qhov tsawg kawg nkaus ua tau yuav tsum tau sau tseg lossis faib tawm ib zaug txhawm rau txo qis qhov muaj peev xwm ntawm kev siv tshuaj ntau dhau.

Mob Tshaj

Qhov tshwm sim ntawm kev siv tshuaj ntau dhau suav nrog kev nyob tsis tswm, tshee hnyo, hyperreflexia, ua pa nrawm, tsis meej pem, ua phem, ua rau pom kev tsis meej, thiab ceeb ntshai. Kev qaug zog thiab kev nyuaj siab feem ntau ua raws lub hauv paus kev txhawb siab. Cov teeb meem plawv muaj xws li arrhythmia, kub siab lossis hypotension, thiab kev vau vau. Cov tsos mob ntawm txoj hnyuv muaj xws li xeev siab, ntuav, raws plab thiab mob plab. Kev siv tshuaj ntau dhau ntawm cov tshuaj sib xws zoo sib xws tau ua rau cov neeg tuag taus feem ntau ua rau ntuav thiab tsis nco qab.

Kev tswj ntawm Phentermine hydrochloride mob hnyav ua rau muaj mob loj thiab suav nrog lavage thiab sedation nrog barbiturate. Kev paub nrog hemodialysis lossis kev lim ntshav peritoneal tsis txaus los tso cai pom zoo hauv qhov no. Acidification ntawm cov zis nce Phentermine excretion. Kev tso tshuaj phentolamine (Regitine® ib, CIBA) tau tawm tswv yim txog ntawm thaj chaw kws tshuaj rau qhov ua tau kom mob hnyav, kub siab, yog tias qhov no ua rau muaj kev noj ntau dhau.

Mob Cawv

Qhov tshwm sim ntawm kev qaug cawv ntev ntev nrog cov tshuaj anorectic suav nrog dermatoses hnyav, cim kev pw tsaug zog, chim siab, ua rau neeg tsis haum xeeb thiab hloov tus kheej. Qhov tshwm sim hnyav tshaj plaws ntawm kev qaug cawv ntev ntev yog kev puas siab puas ntsws, feem ntau hauv tsev kho mob tsis paub qhov txawv ntawm tus mob schizophrenia. SaibTshuajKev tsim txom thiab kev vam khom ( 9.3 ).

Kev piav qhia Phentermine


Phentermine hydrochloride USP yog kev mob siab rau amine anorectic. Nws muaj lub npe tshuaj ntawm α, α, -Dimethylphenethylamine hydrochloride. Cov qauv txheej txheem yog raws li hauv qab no:




Phentermine hydrochloride yog dawb, tsis muaj ntxhiab, hygroscopic, crystalline hmoov uas yog cov dej hauv cov dej thiab cov cawv qis, me ntsis soluble hauv chloroform thiab tsis yaj hauv ether.

Phentermine hydrochloride, tus neeg sawv cev anorectic rau kev tswj hwm qhov ncauj, muaj nyob hauv ntsiav tshuaj uas muaj 37.5 mg ntawm Phentermine hydrochloride (sib npaug rau 30 mg ntawm Phentermine puag).

Txhua lub ntsiav tshuaj muaj cov khoom xyaw tsis ua haujlwm hauv qab no: hmoov txhuv nplej siab, lactose anhydrous, microcrystalline cellulose, colloidal silicon dioxide, stearic acid, magnesium stearate thiab xiav qab zib spheres.

Phentermine - Clinical Pharmacology

Mechanism of Action

Phentermine yog amine sympathomimetic nrog cov tshuaj ua haujlwm zoo ib yam li cov tshuaj thawj ntawm cov chav kawm no siv hauv kev rog, amphetamine (d- thiab dll-amphetamine). Cov tshuaj ntawm chav kawm no siv hauv kev rog feem ntau paub tias yog anorectics lossis anorexigenics. Nws tsis tau raug tsim tawm tias thawj qhov kev txiav txim ntawm cov tshuaj no hauv kev kho rog rog yog ib qho kev nqhis nqhis vim tias lwm qhov kev ua haujlwm hauv nruab nrab lub paj hlwb, lossis cuam tshuam txog kev zom zaub mov, kuj tseem tuaj yeem koom nrog.

Pharmacodynamics

Kev ua yeeb yam ntawm amphetamines suav nrog kev txhawb nqa lub hauv nruab nrab lub paj hlwb thiab nce ntshav siab. Tachyphylaxis thiab kev ua siab ntev tau pom nrog txhua yam tshuaj hauv chav kawm no uas tau pom cov xwm txheej no.

Pharmacokinetics

Ua raws li kev tswj hwm ntawm Phentermine, Phentermine nce mus txog qhov siab tshaj plaws (C.max max ua) tom qab 3 txog 4.4 teev.

nqi ntawm norco 5 325

Cov Pej Xeem Tshwj Xeeb

Lub raum tsis zoo

Kev tso zis ntau dhau ntawm Phentermine nyob rau hauv kev tswj tsis tau cov zis pH yog 62% txog 85%.

Kev raug mob ntawm Phentermine tuaj yeem nce mus txog 91%, 45%, thiab 22%hauv cov neeg mob uas mob hnyav, nruab nrab, thiab mob raum tsis zoo, feem [saib Dosage thiab Administration ( 2.2 ) thiab Siv Hauv Cov Pej Xeem Tshwj Xeeb ( 8.6 )].

Kev Sib Tham Tshuaj

Hauv kev tshawb fawb ib zaug piv rau kev nthuav tawm tom qab kev tswj hwm qhov ncauj ntawm kev sib xyaw ua ke ntawm 15 mg Phentermine thiab 92 mg topiramate rau kev nthuav tawm tom qab kev tswj hwm qhov ncauj ntawm 15 mg Phentermine capsule lossis 92 mg topiramate capsule, tsis muaj qhov hloov pauv tseem ceeb topiramate nyob rau hauv lub xub ntiag ntawm Phentermine. Txawm li cas los xij thaum muaj cov tshuaj topiramate, Phentermine Cmax thiab AUC nce 13% thiab 42%, feem.

Nonclinical Toxicology

Carcinogenesis & Mutagenesis & Kev Txom Nyem Ntawm Fertility

Cov kev tshawb fawb tsis tau ua nrog Phentermine los txiav txim siab qhov muaj peev xwm ua rau carcinogenesis, kev hloov pauv lossis ua tsis taus ntawm kev muaj menyuam.

Kev Kho Mob

Hauv kev soj ntsuam kuaj mob lub sijhawm luv, cov neeg laus rog rog qhia hauv kev tswj kev noj zaub mov thiab kho nrog cov tshuaj anorectic poob ntau qhov hnyav ntawm qhov nruab nrab ntau dua li cov kho nrog cov placebo thiab noj zaub mov.

Qhov loj ntawm qhov hnyav nce ntawm cov neeg mob kho tshuaj ntau dua cov neeg siv tshuaj placebo tsuas yog ib feem ntawm phaus ib lub lim tiam. Tus nqi ntawm kev poob phaus yog qhov zoo tshaj plaws hauv thawj lub lim tiam ntawm kev kho mob rau cov tshuaj thiab cov placebo thiab ua rau txo qis hauv lub lis piam ua tiav. Lub hauv paus tuaj yeem ua rau poob phaus ntau ntxiv vim muaj ntau yam tshuaj cuam tshuam tsis tau tsim. Tus nqi poob phaus cuam tshuam nrog kev siv tshuaj anorectic sib txawv los ntawm kev sim mus rau kev sim, thiab qhov hnyav nce ntxiv zoo li muaj feem cuam tshuam nrog ib feem ntawm qhov sib txawv uas tsis yog cov tshuaj tau teev tseg, xws li kws kho mob-kws tshawb fawb, cov pej xeem kho thiab kev noj zaub mov noj. Cov kev tshawb fawb tsis tso cai cov lus xaus raws li qhov txheeb ze qhov tseem ceeb ntawm cov tshuaj thiab yam tsis yog yeeb tshuaj ntawm kev poob phaus.

doc q lace 100mg tsiav tshuaj

Lub keeb kwm ntawm kev rog yog ntsuas ntau xyoo, qhov kev tshawb fawb tau hais raug txwv rau ob peb lub lis piam ntev; yog li, qhov cuam tshuam tag nrho ntawm kev poob tshuaj hnyav dhau ntawm kev noj zaub mov ib leeg yuav tsum tau txiav txim siab hauv tsev kho mob txwv.

Kev Muab/Cia thiab Ua Li Cas

Phentermine Hydrochloride Tablets, USP 37.5 mg yog cov dawb oval zoo li cov ntsiav tshuaj bisected nrog cov xim xiav, debossed nrog 810 ntawm ob sab sib cais.

Cov ntsiav tshuaj tau ntim rau hauv fwj ntawm 100 (NDC 42806-810-01); thiab 1000 (NDC 42806-810-10).

Khaws cia ntawm 20 ° txog 25 ° C (68 ° txog 77 ° F) [Saib USP Chav Tswj Kub Kub].

Muab faib rau hauv lub thawv kaw nruj raws li tau hais tseg hauv USP, nrog rau kev tiv thaiv menyuam yaus (raws li xav tau).

Tsis txhob ncav cuag cov menyuam.

Cov Lus Qhia Tus Neeg Mob

Cov neeg mob yuav tsum tau ceeb toom tias Phentermine hydrochloride yog lub sijhawm luv (ob peb lub lis piam) nyob rau hauv cov txheej txheem ntawm kev txo qhov hnyav raws li kev tawm dag zog, kev hloov tus cwj pwm thiab kev txwv tsis pub muaj caloric hauv kev tswj cov rog dhau los, thiab kev tswj hwm Phentermine nrog lwm cov tshuaj rau qhov hnyav tsis tau pom zoo [saibKev Qhia thiab Kev Siv ( 1 )thiabCeeb Toom thiab Ceev faj ( 5.1 )].

Cov neeg mob yuav tsum tau qhia paub ntau npaum li cas Phentermine noj, thiab thaum twg thiab yuav siv nws li cas [saibDosage thiab Administration ( 2 )].

Qhia cov poj niam cev xeeb tub thiab niam laus tsis txhob siv Phentermine [saibSiv Hauv Cov Pej Xeem Tshwj Xeeb ( 8.1 , 8.3 )].

Cov neeg mob yuav tsum tau ceeb toom txog kev pheej hmoo ntawm kev siv Phentermine (suav nrog cov kev pheej hmoo tham hauv Kev Ceeb Toom thiab Kev Tiv Thaiv), txog cov tsos mob ntawm qhov tshwm sim tsis zoo thiab thaum mus cuag kws kho mob thiab/lossis nqis tes ua lwm yam. Cov kev pheej hmoo suav nrog, tab sis tsis txwv rau:

  • Kev loj hlob ntawm thawj cov ntshav siab [saibCeeb toom thiabCov kev ceev faj ( 5.2 )]
  • Kev loj hlob ntawm kab mob plawv loj heev [saibCeeb toom thiabCov kev ceev faj ( 5.3 )]
  • Kev cuam tshuam ntawm kev muaj peev xwm koom nrog hauv cov haujlwm uas muaj kev phom sij [saibCeeb Toom thiab Ceev faj ( 5.5 )]
  • Txoj kev pheej hmoo ntawm kev nce ntshav siab [saibCeeb Toom thiab Ceev faj( 5.8 )thiabCov Teeb Meem Tsis Zoo ( 6 )]
  • Txoj kev pheej hmoo ntawm kev sib cuam tshuam [saibContraindications ( 4 ), Ceeb toom thiabCov kev ceev faj ( 5.7 , 5.9 )thiabKev Sib Tham Tshuaj ( 7 )]

Saib ntxiv, piv txwv li,Cov Teeb Meem Tsis Zoo ( 6 )thiabSiv tshwj xeebPejxeem ( 8 ).

Cov neeg mob yuav tsum tau qhia paub txog

  • lub peev xwm los tsim kev ua siab ntev thiab ua yog tias lawv xav tias txhim kho kev ua siab ntev [saibCeeb Toom thiab Ceev faj ( 5.4 )] thiab
  • qhov kev pheej hmoo ntawm kev vam khom thiab muaj peev xwm tshwm sim ntawm kev tsim txom [saibCeeb Toom thiab Ceev faj ( 5.6 ), Kev tsim txom yeeb tshuaj thiab kev vam khom ( 9 ),thiabTshaj dhau ( 10 )].

Qhia rau cov neeg mob kom Phentermine nyob hauv qhov chaw nyab xeeb los tiv thaiv tub sab, raug xwm txheej ntau dhau, siv tsis raug lossis raug tsim txom. Kev muag lossis muab tshuaj Phentermine tuaj yeem ua rau lwm tus mob thiab ua txhaum txoj cai.

Txhua lub cim lag luam yog khoom ntiag tug ntawm lawv tus tswv.

Faib los ntawm:

Epic Pharma, LLC, UA
Laurelton, NY 11413

Rev. 03-2020-00
MF810REV03/20

SIB 1581

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

NDC 42806-810-01
CIV
Phentermine HCl Tablets, USP 37.5 mg

100 TABLETS
Rx xwb







Phentermine HYDROCHLORIDE
Phentermine hydrochloride ntsiav tshuaj
Khoom Qhia
Yam Khoom HLOOV KEV POV THAWJ DRUG LABEL Yam Khoom (Qhov Chaw) NDC: 42806-810
Txoj Kev Tswj QAUV Teem caij DEA CIV
Cov khoom xyaw nquag/nquag muaj nuj nqis
Lub Npe Lub Npe Lub hauv paus ntawm Kev Muaj Zog Lub zog
Phentermine HYDROCHLORIDE (Phentermine) Phentermine HYDROCHLORIDE 37.5mg ib
Cov khoom xyaw tsis haum
Lub Npe Lub Npe Lub zog
STARCH, KEV
MAGNESIUM STEARATE
CELLULOSE, MICROCRYSTALLINE
STEARIC ACID
SUCROSE
ANHYDROUS LACTOSE
SILICON DIOXIDE Cov
Yam Khoom
Xim WHITE (Xiav Tshwj Xeeb) Cov qhab nia 2 qab
Zoo OVAL Loj 11 hli
Tsw Txoj Cai Luam Tawm 810
Muaj
Ntim
# Khoom Code Cov lus piav qhia pob
1 NDC: 42806-810-01 100 TABLET hauv 1 lub raj mis
2 NDC: 42806-810-10 1000 TABLET hauv 1 lub raj mis
Cov Lus Qhia Txog Kev Lag Luam
Qeb Qeb Naj Npawb Daim Ntawv Thov lossis Monograph Citation Hnub Pib Ua Lag Luam Hnub Kawg Ua Lag Luam
Koj TIAB SA040190 01/05/2014
Daim ntawv lo -Epic Pharma, LLC (827915443)
Sau npe -Elite Laboratories, Inc. (785398728)
Tsim
Lub Npe Chaw nyob ID/FEI Kev ua haujlwm
Elite Laboratories, Inc. 785398728 tsim khoom (42806-810)
Epic Pharma, LLC, UA

Kev Tsis Pom Zoo Kho Mob